Although a 2013 guideline recommended statin use to more than 65% of adults with CKD, only about 36% of adults with CKD were taking a statin in 2011-2014.
The investigational drug appeared safe and effective in 3 phase 2b trials.
Investigators report a significant 27% increased risk of Parkinson's disease among individuals aged 65 years and older but less than 75 years.
Spironolactone improved cardiovascular outcomes in heart failure patients with chronic kidney disease, but increased their risk of hyperkalemia.
In a study of patients with chronic kidney disease, the technique for sequencing protein-coding genes yielded a genetic diagnosis in 9.3% of cases.
In a Spanish study, the highest vs lowest tertile of dietary zinc intake was associated with a significant 66% increased relative risk of low-grade prostate cancer.
Sex, high and low baseline potassium levels, and reduced renal function independently predict hyper- and hypokalemia in patients with heart failure.
For example, men with a baseline NLR below 2.5, patients who received abiraterone had a significant 28% decreased risk of death.
In a study of adults with mild-to-moderate chronic kidney disease, women had a significant 28% decreased risk of end-stage renal disease compared with men.
Patients with muscle-invasive bladder cancer had a 22% decreased risk of disease progression if they received neoadjuvant rather than adjuvant chemotherapy, a study found.
In a large retrospective study, the risk of end-stage renal disease was 6-fold higher in patients with Crohn's disease compared with controls.
Study implicates growing prevalence of metabolic and dietary risk factors as important contributors to increases in CKD burden.
Men with Gleason score 9 to 10 prostate cancer derive no significant survival benefit from androgen deprivation therapy.
Patient selection and physician-patient commitment to careful follow-up surveillance are key.
The 3-year survival rate was 81% for patients who underwent EBRT plus standard care vs 73% for those who had standard care alone.
A study of new dialysis patients showed that home hemodialysis was associated with a 23% decreased risk of death at 1 year compared with in-center hemodialysis.
In a propensity score-matched analysis, AKI was associated with a 3.4-fold greater risk of dementia.
Study reveals an 11% prevalence of active gout among solid organ transplant recipients overall and a 13% prevalence among kidney transplant recipients.
Highest vs lowest quartile of intact fibroblast growth factor 23 is associated with a 2-fold greater risk of a first fall in older patients.
Marijuana users with chronic kidney disease experienced a significantly greater annual decline in estimated glomerular filtration rate than non-users, study finds.
Higher levels of urinary oxalate excretion in patients with chronic kidney disease are associated with an increased risk of end-stage renal disease and chronic kidney disease progression.
In the first year after starting dialysis, women have 16% increased odds of major adverse cardiovascular events compared with men.
Long-term data show a local disease recurrence rate of 2.1% at 10 years.
Among prostate cancer patients, androgen deprivation therapy (ADT) recipients are 34% more likely to experience any osteoporotic fracture than those who do not receive ADT.
In a study, androgen deprivation therapy did not increase risks for vascular or any other form of dementia among men with prostate cancer who underwent definitive radiation therapy.
A combination of age, comorbidity, and PSA doubling time can risk stratify cause of death among men with non-metastatic castration-resistant prostate cancer, study suggests.
Propensity score-matched analysis shows that radical and partial nephrectomy for cT1 renal cell carcinoma are associated with similar cancer-specific and all-cause mortality, a study found.
Use of proton pump inhibitors among patients on hemodialysis increased their risk of hip fractures by 19%, study finds.
Older age, male sex, and higher T stage are associated with an increased risk of having bone metastases at initial diagnosis of renal cell carcinoma, study finds.
Both younger age and more recent exposure to some antibiotics were associated with greater risks for kidney stones.
Men and women who smoke are at 2.3-fold and 2.7-fold increased risk of bladder cancer compared with non-smokers.
In a study, increases in red blood cell distribution width during the first year of dialysis was associated with greater risks for death.
Identifying a patient's preferences and goals leads to a care plan that can reflect those goals, and this may improve patient satisfaction.
Thicker bladder wall and a tower-shaped curve on uroflowmetry are associated with shorter healing periods among pediatric patients with overactive bladder.
According to the EDGE Research consortium, both techniques should be in the armamentarium of the urologist.
Among patients on peritoneal dialysis, the odds of death are 32% lower among those with vs without autosomal dominant polycystic kidney disease, meta-analysis finds.
Treatment with a novel urea formulation that is available in the United States safely improves plasma sodium levels, small study shows.
Among patients younger than 40, the prevalence of end-stage renal disease secondary to ADPKD was 9.94% among non-Hispanic blacks vs 7.68% among non-Hispanic whites.
Study shows that the risk of recurrence after salvage radiotherapy is inversely related to the number of nodes resected at radical prostatectomy.
In the most comprehensive study of its kind, investigators find that acute kidney injury not requiring hospitalization is associated with a 90% increased mortality risk.
Use of 5-alpha-reductase inhibitors before and after diagnosis of the malignancy is associated with a 15% and 22% decreased risk of bladder cancer mortality, respectively.
Individuals who had a stroke or transient ischemic attack at age 60 to 64 had a 2-fold higher risk of UUI at age 68 years, a British study found.
Findings from a large study of men in the United Kingdom do not support single PSA testing for population-based screening.
A large study of middle-aged men found that testosterone replacement therapy is associated with a small but significant decrease in cardiovascular risk and an increased risk of obstructive sleep apnea.
Overall treatment success occurred in 98.4% of patients receiving meropenem-vaborbactam vs 94% for those receiving piperacillin-tazobactam.
In multivariable analyses, CKD stage G3b or higher was significantly associated with worse progression-free and cancer-specific survival.
Dialysis patients receiving more or less than 200 mg per month of IV iron had similar risks of death, infection, cardiovascular disease, and hospitalization, meta-analysis shows.
One possible explanation is that increased plasma levels of uremic solutes resulting from kidney disease may impair synaptic development.
Multiparametic MRI findings added to conventional clinical predictors decreases the number of false-positive biopsy results without increasing the number of clinically significant tumors left undiagnosed, study finds.
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)