General News

Statins Underused by Adults With Chronic Kidney Disease

Statins Underused by Adults With Chronic Kidney Disease

By

Although a 2013 guideline recommended statin use to more than 65% of adults with CKD, only about 36% of adults with CKD were taking a statin in 2011-2014.

Molidustat Promising for Renal Anemia

Molidustat Promising for Renal Anemia

By

The investigational drug appeared safe and effective in 3 phase 2b trials.

Gout Linked to Elevated Risk of Parkinson's Disease

Gout Linked to Elevated Risk of Parkinson's Disease

By

Investigators report a significant 27% increased risk of Parkinson's disease among individuals aged 65 years and older but less than 75 years.

Spironolactone Helps HF Patients With CKD, But Ups Hyperkalemia Risk

Spironolactone Helps HF Patients With CKD, But Ups Hyperkalemia Risk

By

Spironolactone improved cardiovascular outcomes in heart failure patients with chronic kidney disease, but increased their risk of hyperkalemia.

Exome Sequencing Zeroes in on Genetic Diagnoses in CKD

Exome Sequencing Zeroes in on Genetic Diagnoses in CKD

By

In a study of patients with chronic kidney disease, the technique for sequencing protein-coding genes yielded a genetic diagnosis in 9.3% of cases.

Prostate Cancer Possibly Linked to Zinc Intake

Prostate Cancer Possibly Linked to Zinc Intake

By

In a Spanish study, the highest vs lowest tertile of dietary zinc intake was associated with a significant 66% increased relative risk of low-grade prostate cancer.

Dyskalemia Common in Heart Failure

Dyskalemia Common in Heart Failure

By

Sex, high and low baseline potassium levels, and reduced renal function independently predict hyper- and hypokalemia in patients with heart failure.

Abiraterone Outcomes Tied to NLR

Abiraterone Outcomes Tied to NLR

By

For example, men with a baseline NLR below 2.5, patients who received abiraterone had a significant 28% decreased risk of death.

Chronic Kidney Disease Progression Risk Lower in Women

Chronic Kidney Disease Progression Risk Lower in Women

By

In a study of adults with mild-to-moderate chronic kidney disease, women had a significant 28% decreased risk of end-stage renal disease compared with men.

Neoadjuvant Chemotherapy for MIBC Ups Disease-Free Survival

Neoadjuvant Chemotherapy for MIBC Ups Disease-Free Survival

By

Patients with muscle-invasive bladder cancer had a 22% decreased risk of disease progression if they received neoadjuvant rather than adjuvant chemotherapy, a study found.

Kidney Failure Risk Greater in Patients With Crohn's Disease

Kidney Failure Risk Greater in Patients With Crohn's Disease

By

In a large retrospective study, the risk of end-stage renal disease was 6-fold higher in patients with Crohn's disease compared with controls.

Chronic Kidney Disease Burden Increasing in the US

Chronic Kidney Disease Burden Increasing in the US

By

Study implicates growing prevalence of metabolic and dietary risk factors as important contributors to increases in CKD burden.

ADT May Be Less Beneficial for Gleason 9 to 10 Prostate Cancer

ADT May Be Less Beneficial for Gleason 9 to 10 Prostate Cancer

By

Men with Gleason score 9 to 10 prostate cancer derive no significant survival benefit from androgen deprivation therapy.

Prostate Cancer Focal Ablation Can Be a Reasonable Option

Prostate Cancer Focal Ablation Can Be a Reasonable Option

By

Patient selection and physician-patient commitment to careful follow-up surveillance are key.

Radiation Ups Survival When PCa Metastatic Burden Is Low

Radiation Ups Survival When PCa Metastatic Burden Is Low

By

The 3-year survival rate was 81% for patients who underwent EBRT plus standard care vs 73% for those who had standard care alone.

Home Hemodialysis May Offer Better Survival

Home Hemodialysis May Offer Better Survival

By

A study of new dialysis patients showed that home hemodialysis was associated with a 23% decreased risk of death at 1 year compared with in-center hemodialysis.

Acute Kidney Injury Increases Dementia Risk

Acute Kidney Injury Increases Dementia Risk

By

In a propensity score-matched analysis, AKI was associated with a 3.4-fold greater risk of dementia.

High Gout Burden Found Among Solid Organ Transplant Recipients

High Gout Burden Found Among Solid Organ Transplant Recipients

By

Study reveals an 11% prevalence of active gout among solid organ transplant recipients overall and a 13% prevalence among kidney transplant recipients.

High FGF23 Increases Fall Risk in CKD

High FGF23 Increases Fall Risk in CKD

By

Highest vs lowest quartile of intact fibroblast growth factor 23 is associated with a 2-fold greater risk of a first fall in older patients.

Marijuana Use by CKD Patients May Hasten Renal Function Decline

Marijuana Use by CKD Patients May Hasten Renal Function Decline

By

Marijuana users with chronic kidney disease experienced a significantly greater annual decline in estimated glomerular filtration rate than non-users, study finds.

Kidney Failure Risk Linked to Oxalate Excretion

Kidney Failure Risk Linked to Oxalate Excretion

By

Higher levels of urinary oxalate excretion in patients with chronic kidney disease are associated with an increased risk of end-stage renal disease and chronic kidney disease progression.

Cardiovascular Event Risk in Dialysis Patients Higher Among Women

Cardiovascular Event Risk in Dialysis Patients Higher Among Women

By

In the first year after starting dialysis, women have 16% increased odds of major adverse cardiovascular events compared with men.

LDR Brachytherapy for PCa Yields Excellent Outcomes

LDR Brachytherapy for PCa Yields Excellent Outcomes

By

Long-term data show a local disease recurrence rate of 2.1% at 10 years.

Prostate Cancer ADT Ups Osteoporotic Fracture Risk

Prostate Cancer ADT Ups Osteoporotic Fracture Risk

By

Among prostate cancer patients, androgen deprivation therapy (ADT) recipients are 34% more likely to experience any osteoporotic fracture than those who do not receive ADT.

Dementia Not Linked to ADT for Prostate Cancer

Dementia Not Linked to ADT for Prostate Cancer

By

In a study, androgen deprivation therapy did not increase risks for vascular or any other form of dementia among men with prostate cancer who underwent definitive radiation therapy.

Simple Clinical Factors May Aid Prognosis in nmCRPC

Simple Clinical Factors May Aid Prognosis in nmCRPC

By

A combination of age, comorbidity, and PSA doubling time can risk stratify cause of death among men with non-metastatic castration-resistant prostate cancer, study suggests.

Radical, Partial Nephrectomy Do Not Differ in Survival Outcomes

Radical, Partial Nephrectomy Do Not Differ in Survival Outcomes

By

Propensity score-matched analysis shows that radical and partial nephrectomy for cT1 renal cell carcinoma are associated with similar cancer-specific and all-cause mortality, a study found.

Hemodialysis Patient Hip Fracture Risk Linked to PPIs

Hemodialysis Patient Hip Fracture Risk Linked to PPIs

By

Use of proton pump inhibitors among patients on hemodialysis increased their risk of hip fractures by 19%, study finds.

Risk Factors for Bone Metastases at RCC Diagnosis Identified

Risk Factors for Bone Metastases at RCC Diagnosis Identified

By

Older age, male sex, and higher T stage are associated with an increased risk of having bone metastases at initial diagnosis of renal cell carcinoma, study finds.

Kidney Stones Linked to Oral Antibiotics

Kidney Stones Linked to Oral Antibiotics

By

Both younger age and more recent exposure to some antibiotics were associated with greater risks for kidney stones.

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

By

Men and women who smoke are at 2.3-fold and 2.7-fold increased risk of bladder cancer compared with non-smokers.

Change in Red Blood Cell Distribution Width Tied With Mortality in HD

Change in Red Blood Cell Distribution Width Tied With Mortality in HD

By

In a study, increases in red blood cell distribution width during the first year of dialysis was associated with greater risks for death.

What a Building Contractor Taught Me About Informed Consent

What a Building Contractor Taught Me About Informed Consent

By

Identifying a patient's preferences and goals leads to a care plan that can reflect those goals, and this may improve patient satisfaction.

Predictors of Pediatric OAB Healing Time Identified

Predictors of Pediatric OAB Healing Time Identified

By

Thicker bladder wall and a tower-shaped curve on uroflowmetry are associated with shorter healing periods among pediatric patients with overactive bladder.

Dusting vs Basketing During Ureteroscopy

Dusting vs Basketing During Ureteroscopy

By

According to the EDGE Research consortium, both techniques should be in the armamentarium of the urologist.

ADPKD Linked to Lower Mortality in Peritoneal Dialysis Patients

ADPKD Linked to Lower Mortality in Peritoneal Dialysis Patients

By

Among patients on peritoneal dialysis, the odds of death are 32% lower among those with vs without autosomal dominant polycystic kidney disease, meta-analysis finds.

Urea Found Safe and Effective for Hyponatremia

Urea Found Safe and Effective for Hyponatremia

By

Treatment with a novel urea formulation that is available in the United States safely improves plasma sodium levels, small study shows.

ADPKD-Related Kidney Failure Occurs Earlier in Non-Hispanic Blacks

ADPKD-Related Kidney Failure Occurs Earlier in Non-Hispanic Blacks

By

Among patients younger than 40, the prevalence of end-stage renal disease secondary to ADPKD was 9.94% among non-Hispanic blacks vs 7.68% among non-Hispanic whites.

More Extensive Lymph Node Dissection in PCa Improves Outcomes

More Extensive Lymph Node Dissection in PCa Improves Outcomes

By

Study shows that the risk of recurrence after salvage radiotherapy is inversely related to the number of nodes resected at radical prostatectomy.

Outpatient AKI Is a Risk Factor for Death, Adverse Renal Outcomes

Outpatient AKI Is a Risk Factor for Death, Adverse Renal Outcomes

By

In the most comprehensive study of its kind, investigators find that acute kidney injury not requiring hospitalization is associated with a 90% increased mortality risk.

Bladder Cancer Mortality in Men Lower With 5-ARI Use

Bladder Cancer Mortality in Men Lower With 5-ARI Use

By

Use of 5-alpha-reductase inhibitors before and after diagnosis of the malignancy is associated with a 15% and 22% decreased risk of bladder cancer mortality, respectively.

Urgency Urinary Incontinence Linked to Previous Stroke

Urgency Urinary Incontinence Linked to Previous Stroke

By

Individuals who had a stroke or transient ischemic attack at age 60 to 64 had a 2-fold higher risk of UUI at age 68 years, a British study found.

Single PSA Screening Has No Effect on Prostate Cancer Mortality

Single PSA Screening Has No Effect on Prostate Cancer Mortality

By

Findings from a large study of men in the United Kingdom do not support single PSA testing for population-based screening.

Testosterone Replacement Therapy Does Not Raise CV Risks

Testosterone Replacement Therapy Does Not Raise CV Risks

By

A large study of middle-aged men found that testosterone replacement therapy is associated with a small but significant decrease in cardiovascular risk and an increased risk of obstructive sleep apnea.

Meropenem-vaborbactam Superior for Complicated UTIs

Meropenem-vaborbactam Superior for Complicated UTIs

By

Overall treatment success occurred in 98.4% of patients receiving meropenem-vaborbactam vs 94% for those receiving piperacillin-tazobactam.

Advanced CKD Linked to Worse Radical Cystectomy Outcomes

Advanced CKD Linked to Worse Radical Cystectomy Outcomes

By

In multivariable analyses, CKD stage G3b or higher was significantly associated with worse progression-free and cancer-specific survival.

Higher-Dose IV Iron Appears Safe in Dialysis

Higher-Dose IV Iron Appears Safe in Dialysis

By

Dialysis patients receiving more or less than 200 mg per month of IV iron had similar risks of death, infection, cardiovascular disease, and hospitalization, meta-analysis shows.

Children With CKD Have Lower IQs

Children With CKD Have Lower IQs

By

One possible explanation is that increased plasma levels of uremic solutes resulting from kidney disease may impair synaptic development.

MRI May Help Cut Down on Unnecessary Prostate Biopsies

MRI May Help Cut Down on Unnecessary Prostate Biopsies

By

Multiparametic MRI findings added to conventional clinical predictors decreases the number of false-positive biopsy results without increasing the number of clinically significant tumors left undiagnosed, study finds.

Renal and Urology News Articles

Sign Up for Free e-newsletters