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Prostate Cancer Prostate Cancer Risk After Single Negative Biopsy Quantified

Prostate Cancer Risk After Single Negative Biopsy Quantified

Men with a single negative prostate biopsy have a 20-year cumulative rate of prostate cancer diagnosis of 23.7%.

Prostate Cancer Online Calculator May Aid In Individualizing Prostate Cancer Care

Online Calculator May Aid In Individualizing Prostate Cancer Care

New tool promises to help patients decide whether radical prostatectomy or radiation therapy is their best treatment option.

Urinary Tract Infections (UTI) Fosfomycin Promising for Chronic Bacterial Prostatitis

Fosfomycin Promising for Chronic Bacterial Prostatitis

Findings from a small study suggest it could be an effective, safe, and attractive alternative to fluoroquinolones, bacterial resistance to which is becoming increasingly prevalent.

Urinary Tract Infections (UTI) Study Supports Once-Daily Plazomicin Use for Complicated UTIs

Study Supports Once-Daily Plazomicin Use for Complicated UTIs

Investigators observe higher rates of clinical cure or microbiologic eradication in patients treated with plazomicin vs meropenem, including those with infections due to Enterobacteriaceae not susceptible to aminoglycosides.

Prostate Cancer Clinicians Somewhat Favor Shared Decision-Making in Older mCRPC Patients

Clinicians Somewhat Favor Shared Decision-Making in Older mCRPC Patients

This survey assessed the opinions of oncologists, urologists, and oncology nurses on the use of shared decision-making in older men with metastatic castration-resistant prostate cancer.

Prostate Cancer Darolutamide Improves Metastasis-Free Survival in CRPC

Darolutamide Improves Metastasis-Free Survival in CRPC

Median metastasis-free survival was longer with darolutamide than with placebo: 40.4 vs 18.4 months.

Prostate Cancer PCa Grade Group Better Predicts Pathologic Outcomes, Recurrence

PCa Grade Group Better Predicts Pathologic Outcomes, Recurrence

In a "real world" study, biopsy and surgical grade groups 2, 3, 4, and 5 each were associated with incrementally higher risks for adverse pathologic features and biochemical recurrence.

Prostate Cancer Guidelines for Germline Genetic Testing in PCa Insufficient

Guidelines for Germline Genetic Testing in PCa Insufficient

A high percentage of men with prostate cancer have 1 or more potentially pathogenic germline variants, but would not be eligible for mutation testing under current NCCN guidelines.

Kidney Stones Predictors of Kidney Stone Recurrence Identified

Predictors of Kidney Stone Recurrence Identified

Risk for recurrence within 5 years varies with risk factors, past episodes, time since last episode.

Prostate Cancer Prostate Cancer Active Surveillance Increasing in the US

Prostate Cancer Active Surveillance Increasing in the US

From 2010 to 2015, active surveillance/watchful waiting increased from 14.5% to 42.1%, according to a new study.

Prostate Cancer Low Carb Diet + Walking May Ease ADT's Adverse Effects

Low Carb Diet + Walking May Ease ADT's Adverse Effects

In a small study, men on androgen deprivation therapy for prostate cancer lost weight and experienced improved hemoglobin A1C and lipid profiles.

Prostate Cancer Good Quality of Life Reported Even in Advanced Prostate Cancer

Good Quality of Life Reported Even in Advanced Prostate Cancer

Men with advanced disease report health-related quality of life similar to that of those with localized disease.

Bladder Cancer Squamous MIBC Histology Predicts Worse Survival

Squamous MIBC Histology Predicts Worse Survival

Squamous cell carcinoma is associated with a 79% increased risk of death compared with urothelial carcinoma in patients with muscle-invasive bladder cancer, study finds.

Prostate Cancer First-Year Post-ADT Weight Loss Predicts Higher PCa Death Risk

First-Year Post-ADT Weight Loss Predicts Higher PCa Death Risk

Weight loss in the first year after starting androgen deprivation therapy in men who have undergone radical surgery for prostate cancer ups the risk of metastatic disease and death from prostate cancer.

Prostate Cancer Longer Androgen Suppression With RT Superior for Advanced PCa

Longer Androgen Suppression With RT Superior for Advanced PCa

Study finds 18 vs 6 months of androgen suppression and radiotherapy for locally advanced prostate cancer is associated with a 30% decreased risk of death from the disease.

Kidney Cancer Obesity-Related Cancers Rising Among Younger Adults

Obesity-Related Cancers Rising Among Younger Adults

Kidney cancer and some other cancers tied to obesity are increasing the most rapidly among individuals younger than 50.

Prostate Cancer Adding Docetaxel to ADT Not Beneficial in High-Risk PCa

Adding Docetaxel to ADT Not Beneficial in High-Risk PCa

In a study of men with nonmetastatic high-risk prostate cancer who have rising PSA after primary therapy, investigators found no significant difference in PSA progression-free survival.

Prostate Cancer Prostate Cancer ADT May Reduce Autoimmune Disease Risk

Prostate Cancer ADT May Reduce Autoimmune Disease Risk

Androgen deprivation therapy recipients had a significantly lower risk for autoimmune diseases overall and for Graves' disease, uveitis, and psoriasis.

Kidney Cancer First-Line TKIs Less Effective in Non-Clear-Cell Renal Cell Carcinoma

First-Line TKIs Less Effective in Non-Clear-Cell Renal Cell Carcinoma

First-line treatment of metastatic renal cell carcinoma with tyrosine kinase inhibitors is associated with worse progression-free and overall survival in patients with non-clear-cell vs clear-cell histology.

Prostate Cancer Finasteride Not Tied to Increase in Prostate Cancer Mortality

Finasteride Not Tied to Increase in Prostate Cancer Mortality

Finasteride tied to lower risk for death from prostate cancer, but lower risk not statistically significant